Mother

Strategy and Synergy
The best artifact for. The reduced is a pretty big cost, but always worth it, because running out of  is impossible. It basically automatically activates all.

This artifact can make a mediocre run increadibly overpowered on pickup, almost always resulting in a Victory. This artifact alone can encourage the player to change the course of your whole run.

Trivia

 * The mechanic was called Earthbound in the demo.
 * The mechanic was called Earthbound in the demo.